What is pancreatic cancer screening ?

The goal of screening is to detect precancerous lesions or cancer at an early stage in individuals who appear healthy.

Since pancreatic cancer is relatively rare, screening is reserved for certain high-risk populations. This includes individuals with more than 2 cases of pancreatic cancer in first-degree relatives, as well as those with more than 3 cases of pancreatic cancer in the family, regardless of the degree of relation. It also includes patients with hereditary chronic pancreatitis or Lynch syndrome. Individuals with a genetic mutation associated with a higher risk of pancreatic cancer will also undergo screening.

At-risk individuals should receive an oncogenetic consultation to more accurately assess their risk and consider screening with MRI or pancreatic endoscopic ultrasound. This procedure involves inserting a flexible tube called an endoscope into the stomach and then the duodenum to deliver ultrasound waves. CT (computed tomography) scans are used only when MRI is contraindicated.

This screening is offered starting at age 50 or 10 years before the youngest family member diagnosed with pancreatic cancer. It will be conducted annually.

Any discovery of diabetes during the follow-up period will prompt imaging to be carried out as soon as possible. In all at-risk individuals, smoking cessation will be strongly recommended, as tobacco is a risk factor for the disease.